Since the mid-1970s, Spirulina production plants have been established in Mexico, the United States, Japan, Israel and China. According to statistics, the annual output of Spirulina platensis in the world was 1000 tons in 1983, and reached about 2000 tons in 1994, doubling and increasing gradually in recent years. Spirulina is rich in nutrients. It is recommended by FAO as "the most ideal food for mankind tomorrow". Its protein content is as high as 50%-70%. Spirulina is an excellent protein source, and the content of phycocyanin can reach 25%-28% of cell dry weight. Phycocyanin is an important active substance in Spirulina platensis. Studies at home and abroad show that Spirulina platensis and its active ingredients have broad application prospects in functional food and drug research and development. Phycocyanin as a photosensitizer for photodynamic therapy of tumors is abundant in resources and inexpensive in price. Therefore, phycocyanin as a photosensitizer will show a good application prospect in photodynamic therapy.
As we all know, cancer is one of the diseases that seriously threaten human health at present. Traditional methods of cancer treatment mainly include surgical resection, radiotherapy and chemotherapy, but these methods often have the defects of easy recurrence and large side effects. In recent years, some potential anti-tumor nutrients have attracted more and more attention of researchers. They have significant inhibitory effects on some specific cancers, and phycocyanin is one of the most important ones. It has the advantages of high safety, strong activity, non-toxic side effects, and can provide new ideas and directions for the treatment of cancer.
Phycocyanin has obvious effect of inhibiting the growth of tumors. It is non-toxic and highly effective. Its mechanism of inhibiting tumors is complex, and its understanding is not yet sufficient, which needs to be further clarified. At the same time, phycocyanin belongs to phycobiliproteins. Because of its extensive role, phycocyanin has been paid more and more attention. A large number of studies on phycocyanin and its biological activity have shown that. Natural phycocyanin has high activity in anti-cancer, anti-oxidation, anti-inflammatory and free radical elimination in vivo to protect the body. It can be widely used in monthly food, dyestuff, cosmetics and other industries. It can also be used as fluorescent reagent, probe or tracer in clinical diagnosis, biochemical engineering and other fields. However, it is rare in the development of functional food and is opened as a drug. Discovery literature research is less, and modern literature research for drug development is less. According to a large number of studies reported, phycocyanin is non-toxic, belongs to the actual non-toxic, and has great potential for the development of drugs and functional foods.
Although phycocyanin is widely used, its content is not high, its stability is general, and it is easy to inactivate in some environments. There are many problems in the development of natural phycocyanin, such as high cost, high impurities, long cycle, low content of active peptide and some difficulties in extraction and purification. Then, algae proteins are enzymatically hydrolyzed to enhance their utilization rate in order to enhance their extensive pharmacological effects. With the development of recombinant DNA technology, the number of intracellular genetic engineering products such as human growth hormone, interleukin and interferon is increasing. The new recombinant phycocyanin can be expressed by genetic engineering. The phycocyanin can be further extensively exploited by new genetic methods to achieve deeper research of natural drugs, so as to fully reflect its value in medicine, food and other aspects and better serve human beings.
In China, the research on Spirulina and phycocyanin began in the 1970s. After more than 30 years of research, great progress has been made, but most of them are at the laboratory level. Binmei Biology is one of the first large-scale industrial enterprises to extract and produce phycocyanin in China. Its technical patents for extracting phycocyanin have broken Japan's international monopoly for more than 20 years. On the one hand, we need to continue to study phycocyanin's physical and chemical characteristics in order to explore its physiological activity; on the other hand, according to the research results, we should expand the development of phycocyanin to its functions. Functional foods and medicines come up in order to make better use of their value.
Linkedin: Connie Chen
Web Site: www.binmeibio.com
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